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(...more...) Tat is produced early after infection and it"s essential for virus replication and infectivity. Tat protein is also immunogenic and antibodies (Ab) against tat have been correlated with delayed disease progression and may exert protective effects inhibiting HIV replication. Moreover, Tat is efficiently taken up by monocyte-derived dendritic cells, promoting their maturation. Finally, murine vaccination with a biologically active tat protein has been shown to be safe and immunogenic.

Recommended dilutions:Recommended starting dilutions can vary lot-to-lot. Consult the product information label in the package for lot specific values.

Note:When using any primary antibody or fluorescence-labelled secondary antibody for the first time, titrate out the antibody to determine which dilution allows the strongest specific signal with the lowest background for your sample.

For untested applications or species please refer to theS.M.A.K.program.

Purity:Polyclonal immunoglobulins purified by affinity chromatography.

Form:Liquid. Supplied in 100mM sodium citrate, 50mM Tris and 0.05% v/v glycerol. Neutral pH.