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商品描述
α-Mangostin
Product Code:
B1059-50
Pack Size:
50 mg
Form:
Biochemicals
Shipping Temp:
gel pack
Storage Temp:
-20°C
Target Species:
Human
Product Type:
Biochemical
Description:
α-Mangostin, a naturally occurring xanthone, displays both fast-binding and slow-binding inhibitions to FAS?in vitro. It inhibits FAS overall reaction with an IC50 value of 5.54?μM noncompetitively with respect to NADPH, and partially competitively against both substrates acetyl-CoA and malonyl-CoA. Its inhibitory activity is higher than classical FAS inhibitors such as C75, EGCG and curcumin. It induces apoptosis in breast cancer cells by inhibition of FAS.
Appearance: Pale yellow to yellow solid
Purity: ≥95% by HPLC
Accession Number: P35219
Supplier:
BioVision
Product Category:
Signalling Pathways - Small Molecules > Inhibitors
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Product Code:
B1059-50 Price (50 mg):
£497.00 excluding VATDiscount available for 2 or more products. Visit Special Offers page for details.
