生物合成/[Asn7]-β-淀粉样蛋白(1-42),Tottori-日本突变/0.5 mg/13795-005

价格
¥5200.00
货号:13795-005
浏览量:127
品牌:Bio-Synthesis
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商品描述
[Asn7] - beta - Amyloid (1 - 42), Tottori - Japanese Mutation
Sequence (1LC):
DAEFRHNSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence (3LC):
NH2 - Asp - Ala - Glu - Phe - Arg - His - Asn - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - COOH
Catalog :
13795-005
Unit:
0.5 mg
Price/Unit:
$260(For other quantities please Contact Us or call 972-420-8505)
Purity:
Purity > 95% by HPLC
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This b-amyloid (1-42) contains the Tottori-Japanese (D7N) mutation where Asp7 is replaced by Asn7. In vitro analysis using beta-amyloid 1 to 40-based mutant peptide reveals that the D7N mutation does not accelerate the nucleation phase but selectively promotes the elongation phase of amyloid fibril formation. The levels of protofibrils generated from D7N beta-amyloid were markedly inhibited despite enhanced fibril formation.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
4513.1 g/mol
Reference/Citations:
  1. Hori, Y. et al. J. Biol. Chem. 282, 4916 (2007).
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寡核苷酸合成Bio-Synthesis是Custom Oligo Synthesis服务的提供商。使用称为亚磷酰胺固相合成的方法,寡核苷酸以未修饰或修饰的化学结构合成,具有确定的序列。使用固相亚磷酰胺化学方法合成的寡核苷酸通常通过高效液相色谱(HPLC)或PAGE纯化,以达到所需的纯度。通过固相合成获得的合成DNA或RNA寡核苷酸可用于各种分子生物学应用中,例如PCR,实时PCR,测序,定点诱变,单核苷酸多态性(SNP)分析,微阵列和各种治疗应用。