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苏州工业园区生物纳米园A4#216
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商品描述
Product information "Rapamycin"
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin inhibitors. Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition. Anti-proliferative. Antitumor compound. Apoptosis enhancer. Activator of autophagy both in vitro and in vivo. Anti-HIV and anti-aging compound. Neuroprotective.
| Keywords: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-CN2-0025-M001 |
Properties
| Application: | MTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| MW: | 914,2 D |
| Formula: | C51H79NO13 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 53123-88-9| Find alternatives |
| KEGG ID : | K07203 | Find alternatives |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution Our products are for laboratory research use only: Not for administration to humans!
