Product ID B3280Cas No.Purity ≥98%

• Description
• Product Info
• Shipping and Storage
• Downloads
• References

Description

Bis(salicyl) fumarate is an aspirin analog that is used to induce hemoglobin chain crosslinks at lysine residues. This compound is used to study hemoglobin function in research models and may be used to develop treatments for sickle-cell anemia. This compound may exhibit anti-inflammatory, analgesic, and antipyretic activities.

Product Info

PurityFormulaFormula Wt.Melting PointAppearance

≥98%

C18H12O8

356.29

178-180°C

White to off white powder

Shipping and Storage

Store TempShip Temp

-20°C

Ambient

Downloads

Info Sheet

B3280 Info Sheet PDF

References

Macdonald VW, Motterlini R. Vasoconstrictor effects in isolated rabbit heart perfused with bis(3,5-dibromosalicyl)fumarate cross-linked hemoglobin (alpha alpha Hb). Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):565-75. PMID: 7994376.

Thompson EB, Klotz IM. Pharmacological actions of diaspirins, potential antisickling agents: analgesic and anti-inflammatory effects. Res Commun Chem Pathol Pharmacol. 1985 Jun;48(3):381-8. PMID: 4023420.

Chatterjee R, Iwai Y, Walder RY, et al. Structural features required for the reactivity and intracellular transport of bis(3,5-dibromosalicyl)fumarate and related anti-sickling compounds that modify hemoglobin S at the 2,3-diphosphoglycerate binding site. J Biol Chem. 1984 Dec 10;259(23):14863-73. PMID: 6501320.

>>> 更多资讯详情请访问蚂蚁淘商城