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蚂蚁淘在线 / 品牌中心 / pblassaysci / PBL/人干扰素αD（α1）/1 x 105units/11125-1

PBL/人干扰素αD（α1）/1 x 105units/11125-1

价格
￥5600.00
货号：11125-1
浏览量：127
品牌：pblassaysci
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商品描述

Human IFN Alpha D (Alpha 1)

Home / Products / Proteins / Interferons / Human IFN Proteins / Human IFN Alpha D (Alpha 1)
Product Features:
  • Human IFN Alpha 1 recombinant protein expressed in E.coli
  • Expression is induced by viral infection
  • Encoding gene IFNA1 at position Val114

Ordering

Catalog No. Pack Size Price Quantity
11125-1

1 x 105 units

$280.00
  • Specifications
  • Tech Info / Data
  • Citations
  • Documentation

Specifications

FormulationSupplied frozen in phosphate-buffered saline (PBS) containing 0.1% Bovine Serum Albumin (BSA)
Molecular Weight19.4 kDa
SourcecDNA obtained from human leukocyte mRNA expressed in E.coli
Purity> 95% by SDS-PAGE stained by Coomassie Blue 
BioactivityMeasured using a cytopathic inhibition assay on Bovine Kidney Cells (MDBK) with Vesicular Stomatis Virus (VSV); human lung carcinoma cell line A549 with encephalomyocarditis virus (EMCV)
StorageFor retention of full activity store at -70 ºC or below and avoid repeated freeze-thaw cycles
SynonymsHu-[Val114] IFN-α1 
Accession NumberV00538

Tech Info / Data

Background:

Recombinant Human Interferon Alpha D (Hu-IFN-alpha D; Hu-[Val114] IFN-alpha 1) obtained from human leukocyte mRNA expressed in E.coli.

IFN alpha 1 is one of the many interferon alpha subtypes belonging to the Type I leukocyte IFN family. The Type I IFN family has antiviral, anti-proliferative and natural killer cell activities.

Citations

3 Citations:

  1. Wilson, Timothy R, et al. (2012). Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 12 pgs. PMID: 22763448. (link)

  2. Wu, TG, et al. (2007). IFN-alpha-induced murine B16 melanoma cancer vaccine cells: induction and accumulation of cell-associated IL-15. Journal of Interferon & Cytokine Research. PMID: 17266439. (link)

  3. Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839. (link)

Documentation

PDF icon 11125-1 Certificate of Analysis (CoA)
PDF icon SDS

Human IFN Alpha D (Alpha 1) Titration in A549

Titration of Human Interferon Alpha D (Alpha 1) in the A549 Cell Line
PBL单克隆抗体和多克隆抗体在某些应用中可以互换。在某些情况下，一种或另一种抗体会产生更好的结果。单克隆抗体在诸如ELISA，流式细胞仪或表位作图等应用中具有很高的特异性，在这些应用中需要特异性结合。多克隆抗体对于中和是优选的，因为它们靶向特定抗原的多种特定表位。 PBL提供了一系列针对来自各种哺乳动物的不同干扰素（IFN）的单克隆和多克隆抗体。与其他市售抗IFN抗体相反，PBL的人IFNα抗体针对多种人IFN亚型进行了测试