- SynonymFABP7,BLBP,B-FABP,FABPB,MRG
- SourceHuman FABP7, His Tag (FA7-H5142) is expressed from E.coli cells. It contains AA Val 2 - Ala 132 (Accession # AAH22499).Predicted N-terminus: MetRequest for sequence
- Molecular Characterization
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 15.7 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
- EndotoxinLess than 1.0 EU per μg by the LAL method.
- Purity
>92% as determined by SDS-PAGE.
- Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
- Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
- Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Human FABP7, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%.
- BackgroundFatty acid-binding protein 7 (FABP7) is also known as Brain-type fatty acid-binding protein (B-FABP), Brain lipid-binding protein (BLBP), Fatty acid-binding protein, brain (FABPB), Mammary-derived growth inhibitor related (MRG). FABP7 / BLBP/ B-FABP belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. FABP7 is expressed in brain and other neural tissues. FABP7 / B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
- References
- (1)Shimizu F., et al., 1997, Biochim. Biophys. Acta 1354:24-28.
- (2)Godbout R., et al., 1998, Oncogene 16:1955-1962.
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