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abbomax/Glucagon/100ug/500-6944

价格
面议
货号:500-6944
浏览量:95
品牌:abbomax
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Glucagon
GLP1, GLP2
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Product Preparation
A synthetic peptide corresponding to the human Glucagon conjugated to carrier protein.
Background
Glucagon is a 29 amino acids polypeptide hormone that is secreted by alpha cells in the islets of Langerhans of endocrine portion of the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), glucagon-like peptide 2 (GLP2), VIP (Vaso-active intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
SPECIFICITY
This antibodyrecognizeshuman Glucagon protein.It also reacts with mouse and rat origins. The other species are not tested.
FORMULATION
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles.
Gene ID
2641
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5µg/ml
IHC
2-10µg/ml
Flow cytometry
5-10µg/ml
abbomax的14-3-3蛋白是一类小而广泛表达的高度保守的胞质蛋白。14-3-3蛋白与包括Raf,PKC,Bad,Cbl和c-Bcr在内的信号转导,细胞周期调控和细胞凋亡的各种分子结合并影响其活动。14-3-3与靶蛋白之间的相互作用受14-3-3与靶蛋白的磷酸化状态强烈影响。14.3.3β在脑组织中高度表达。这对于细胞转化和有丝分裂信号传导至关重要。