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蚂蚁淘在线 / 品牌中心 / Immunoway / Immunoway/Numb (phospho-Ser276) rabbit pAb/20ug 50ug 100ug/YP1424

Immunoway/Numb (phospho-Ser276) rabbit pAb/20ug 50ug 100ug/YP1424

价格
￥1700.00
货号：YP1424
浏览量：127
品牌：Immunoway
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商品描述

Numb (phospho-Ser276)rabbit pAb

  • Catalog No.：YP1424
  • Applications：WB
  • Reactivity：Human
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name：
    • NUMB
    • Protein Name：
    • Numb (Ser276)
    • Human Gene Id：
    • 8650
    • Human Swiss Prot No：
    • P49757
    • Mouse Gene Id：
    • 18222
    • Mouse Swiss Prot No：
    • Q9QZS3
    • Rat Swiss Prot No：
    • Q2LC84
    • Immunogen：
    • Synthesized phosho peptide around human Numb (Ser276)
    • Specificity：
    • This antibody detects endogenous levels ofHuman Numb (phospho-Ser276)
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Rabbit
    • Dilution：
    • WB 1:1000-2000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -20°C/1 year
    • Other Name：
    • Protein numb homolog (h-Numb) (Protein S171)
    • Observed Band(KD)：
    • 70
    • Background：
    • NUMB, endocytic adaptor protein(NUMB) Homo sapiensThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
    • Function：
    • function:Implicated in the control of cell fate decisions during development.,PTM:Isoform 1 and isoform 2 are ubiquitinated by LNX leading to their subsequent proteasomal degradation (By similarity). Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,sequence caution:Intron retention.,similarity:Contains 1 PID domain.,subunit:Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.,
    • Subcellular Location：
    • nucleus,early endosome,plasma membrane,cell-cell adherens junction,focal adhesion,cytoplasmic, membrane-bounded vesicle,basolateral plasma membrane,extrinsic component of plasma membrane,clathrin-coated vesicle,apical part of cell,
    • Expression：
    • B cells,Blood,Brain,Cervix carcinoma,Epithelium,Fetal brain,HeLa cells,Live
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway二抗可与酶，生物素或荧光团偶联，可用于多种基于抗体的应用，包括Western Blot，ImmunoHistoChemistry，ImmunoFluorescence，流式细胞术和ELISA。我们为您的每种应用提供来自山羊，兔和驴的高质量二抗。也可以使用血清吸附的二抗，建议将其用于富含免疫球蛋白的样品。