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Fluorescein Monolysocardiolipin is a fluorescent analog of monolysocardiolipin labeled on the sn-1 acyl chain. Cardiolipin (CL) is an important component of the prokaryotic and eukaryotic inner mitochondrial membrane. In humans, CL is made by cardiolipin synthase from phosphatidylglycerol and cytidinediphosphate-diacylglycerol. Monolysocardiolipin (MCL) is an intermediate in CL remodeling. Acetyl transferase tafazzin mutations impairing linoleic acid transfer to MCL are considered the main reason of Barth syndrome; and autoantibodies to MCL have been found in patients with anti-phospholipid syndrome and lupus. Fluorescent lipids have been used in TLC, electrophoresis, microplatefluorescent assays, and sub-cellular localization experiments.
| Categories | Lipids |
|---|---|
| Filter | Cardiolipin, Fluorescent, Lysophospholipid |
| Excitation/Emission | 494/521 nm |
| Molecular Formula | C68H103NO22P2 |
| Molecular Weight (g/mol) | 1348.49 |
| Purity | >95% |
| Storage | -20 °C or below, protect from light |


