Purifiedanti-LBPAmonoclonalantibody

Subclass:IgG1k(clone6C4)Source:MouseApplications:Immunofluorescence,ELISAStorage:Storeat-20°Cforupto60days.Aliquotandstoreat-20or-70°Ciflongerstorageisnecessary.Avoidrepeatedfreeze/thawcycles.

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ThepurifiedMouseAnti-LBPAantibodyrecognizesanimportantbutunusualeukaryoticlipid,lysobisphosphatidicacid,(LBPA)alsotermedbis(monoacylglyceryl)phosphate(BMP).LBPAisfoundprimarilyinlateendosomesandisacellularMarkerofthiscompartment.Further,LBPAisalipidantigenfortheautoimmunedisorder,anti-phospholipidsyndrome(APS).

FeaturedinPublications:

1)Kobayashi,T.,M.H.Beuchat,etal.(1999).“Lateendosomalmembranesrichinlysobisphosphatidicacidregulatecholesteroltransport.”NatCellBiol1(2):113-8.2)Zornetta,I.,L.Brandi,etal.(2010).“Imagingthecellentryoftheanthraxoedemaandlethaltoxinswithfluorescentproteinchimeras.”CellMicrobiol12(10):1435-45.3)Otomo,T.,K.Higaki,etal.(2011).“LysosomalStorageCausesCellularDysfunctioninMucolipidosisIISkinFibroblasts.”JBiolChem286(40):35283-90.

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TechnicalDataSheet

Categories	Antibodies&Proteins
Filter	Antibody,LBPA,LipidBinding

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