Sphingosine 1-phosphate (S1P) is a bioactive lysophospholipid formed by phosphorylation of sphingosine by sphingosine kinases. S1P binds to five G-protein coupled receptors designated S1P_1-5 leading to cell proliferation, motility, and has a role in regulation cell shape. In addition, S1P acts as an intracellular mediator in a receptor-independent manner regulating cell survival and Ca²⁺ homeostasis.

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Solubility

1 mg/mL warm acetic acid0.3 mg/mL MeOH (alternately vortex for 1 min then sonicate in a bath sonicator for 10 minutes until a clear solution is obtained. Heating the solution (50-65°C) can also help with solubilization)

Bulk quantities of this product are available. Please email echelon@echelon-inc.com for more information.

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Categories	Lipids
Filter	Sphingolipid, Sphingosine 1-phosphate
CAS Number	26993-30-6
Molecular Formula	C18H38NO5P
Molecular Weight (g/mol)	379.5
Purity	95%
Storage	-20 °C or below

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