PurifiedAnti-LysophosphatidicAcid(LPA)monoclonalantibody.Subclass:IgGk₁Source:MouseApplications:ELISA,Immunohistochemistry,Immunocytochemistry

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ProductBackground:LysophosphatidicAcid(LPA)isaserum-derivedphospholipidinvolvedindiverseceullularprocessessuchascellproliferation,chemotaxis,plateletaggregation,woundhealing,angiogensis,tumorinvasion,andsmoothmusclecontraction.RecentresearchindicatesLPAmayplayasignificantroleinthepathophysiologyofcancerandmaybeusedasabioMarkerforovariancancer.TheLysophosphatidicAcidAntibody(504B3)wasoriginallydevelopedandpatentedatLpathTherapeutics.

Storage

Antibodyisstableforupto1yearat-20°C.Antibodyisstablefor60daysat4°C.Avoidrepeatedfreeze/thawcycles.

References

1)J.Cheng,S.Sahani,T.J.Hausrat,etal.(2016)“PreciseSomatotopicThalamocorticalAxonGuidanceDependsonLPA-MediatedPRG-2/RADIxinSignaling”Neuron,92(1);126-142.doi:doi:10.1016/j.neuron.2016.08.0352)M.Balood,H.Zahednasab,etal.(2014)“Elevatedserumlevelsoflysophosphatidicacidinpatientswithmultiplesclerosis”Hum.Immunol.75(5);411-413,doi:10.1016/j.humimm.2014.02.0213)Y.Goldshmit,R.Matteo,etal.(2012)“Blockageoflysophosphatidicacidsignalingimprovesspinalcordinjuryoutcomes.”Am.J.Pathol.,181(3):978-992,doi:10.1016/j.ajpath.2012.06.007

Bulkdiscountsavailable,pleaseemailEchelon@echelon-inc.comforinformation.

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Documents

TechnicalDataSheet

Categories	Antibodies&Proteins
Filter	Antibody,LipidBinding,LysophosphatidicAcid

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