Biorbyt/VHL配体2盐酸盐/2 g/orb611997

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VHL ligand 2 hydrochloride

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Catalog Number: orb611997

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Product Overview
Product Name VHL ligand 2 hydrochloride
Catalog Number orb611997
Hazard InformationNon-Toxic
Target VHL ligand 2 hydrochloride
Product Properties
Storage 2 years -20°C Powder 2 weeks4°C in DMSO6 months-80°C in DMSO
Note For research use only.
Purity >98%
Formula C21H18F3N5O
MW 413.4
CAS Number [1948273-03-7]
SMILES O=C (C1CC1)NC2=CC=CC (NC3=NC=CC (NC4=CC=CC (C (F) (F)F)=C4)=N3)=C2
Chemical Name N-[3-[[4-[[3- (trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanecarboxamide
Activity VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader.
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VHL ligand 2 hydrochloride

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