Isotype: Mouse IgG2ak

Immunogen: Recombinant human IL-2

INFORMATION: The cytokine human interleukin-2 (IL-2) is a 15 kd protein expressed upon activation by peripheral TH1 cells, medullary thymocytes, and a subset of large granular lymphocytes. Secreted IL-2 stimulates proliferation and lymphokine production by T cells, B cells and NK cells. Clone N7-48A binds to intracellular IL-2 in flow cytometry.

References: 1. S.L. Swain (1991) Curr Opin Immunol 3-304-310. 2. A.K. Abbas, et al, (1996) Nature 383: 787-793. 3. A. Rebollo, et al, (1996) Advan Immunol 63: 127-196.

Ancell抗CD105异花青素人CD105（endoglin）是一种同型二聚体膜糖蛋白（1），实际上局限于内皮细胞，并且存在于一些白血病细胞和少量骨髓细胞中。CD105 以高亲和力与TGF- b 1和b 3结合（4）。同种型：鼠IgG1 kappa免疫原：人B谱系白血病细胞的膜制备特异性：抗体SN6识别分子量约为160 kd的人CD105同型二聚体的细胞外表位。据报道它与非人类灵长类动物以及马和猪（11）CD105发生交叉反应。功能应用：抗体SN6将增强TGF-b1与表达CD105的白血病细胞的结合。  抗体SN6已用于鉴定间充质祖细胞群（8,9,10）。