CD273 (B7-DC, PD-L2, Programmed Death Ligand 2) is a 25 kd member of the B7 family and is expressed mainly on a sub set of Dendritic cells. When engaged it has a stimulatory effect on the expressing DC, and delivers a down regulatory signal to cells expressing its counter receptor, CD279(PD-1). The interaction of CD273(B7-DC) and CD274(B7-H1) with their receptor, CD279(PD-1) is an important component of immune regulation.

Isotype: Murine IgG2a Kappa

Immunogen: Recombinant human CD273(B7-DC)

Specificity: Antibody ANC8D12 binds to recombinant CD273 and cell surface CD273 expressed on monocyte derived Dendritic cells (moDC), and blocks binding of recombinant CD279 to CD273 in EIA and FACS.

Ancell抗CD105异花青素人CD105（endoglin）是一种同型二聚体膜糖蛋白（1），实际上局限于内皮细胞，并且存在于一些白血病细胞和少量骨髓细胞中。CD105 以高亲和力与TGF- b 1和b 3结合（4）。同种型：鼠IgG1 kappa免疫原：人B谱系白血病细胞的膜制备特异性：抗体SN6识别分子量约为160 kd的人CD105同型二聚体的细胞外表位。据报道它与非人类灵长类动物以及马和猪（11）CD105发生交叉反应。功能应用：抗体SN6将增强TGF-b1与表达CD105的白血病细胞的结合。  抗体SN6已用于鉴定间充质祖细胞群（8,9,10）。