Human CD270 (Herpes Virus Entry Mediator, TNFRSF14, ATAR, LIGHTR, TR2) is a 36kd type I membrane protein that has been found on a broad range of lymphoid tissues. Its ligands include the TNF Ligand family members LTalpha and LIGHT, and the CD28/Ig Superfamily member BTLA(2).

Isotype: Murine IgG2a Kappa

Immunogen: Recombinant human CD270(HVEM)

Specificity: Antibody ANC3B7 is reactive with recombinant CD270 in EIA, and binds to CD270 present on human U-937 cell surface in Flow Cytometry.

References:

1) Hsu H, et al. (1997) J Biol Chem 272:13471.

2) Gonzalez LC, et al. (2005) PNAS 102(4): 1116-1121.

3) Laszlo G Radvany, Patrick Hwu, et al. (Dec 2012) Clin Cancer Res 18: 6758.

Ancell抗CD105异花青素人CD105（endoglin）是一种同型二聚体膜糖蛋白（1），实际上局限于内皮细胞，并且存在于一些白血病细胞和少量骨髓细胞中。CD105 以高亲和力与TGF- b 1和b 3结合（4）。同种型：鼠IgG1 kappa免疫原：人B谱系白血病细胞的膜制备特异性：抗体SN6识别分子量约为160 kd的人CD105同型二聚体的细胞外表位。据报道它与非人类灵长类动物以及马和猪（11）CD105发生交叉反应。功能应用：抗体SN6将增强TGF-b1与表达CD105的白血病细胞的结合。  抗体SN6已用于鉴定间充质祖细胞群（8,9,10）。