Human CD24 is a glycosyl phosphatidyl inositol (GPI) anchored surface protein found on B cells during multiple stages of development from precursor to the onset of plasma cell differentiation. Expression of CD24 has been observed to be a lineage predictor in AML(5).

Isotype: Murine IgM

Immunogen: Human B lymphocyte tumor cells: NALM-6-M1

Specificity: Antibody BA-1 recognizes a sialic acid-dependent epitope of human CD24 of approximately35/45 kd (1, 3, 4).

References:

1. C.S. Abramson, et al, (1981) J Immunol 126: 83-88.

2. H. Mehmet, et al, (1990) Clin Exp Immunol 81: 489-495.

3. Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 82-84.

4. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 539-543.

5. Raife TJ, Dick FR, et al. (1994) Am J Clin Pathol: 101(3):296-9.

6. L Kelly, NJ Hart, et al. (2001) Am J Pathol 159(1): 285-295. https://doi.org/10.1016/S0002-9440(10)61694-X

Ancell抗CD105异花青素人CD105（endoglin）是一种同型二聚体膜糖蛋白（1），实际上局限于内皮细胞，并且存在于一些白血病细胞和少量骨髓细胞中。CD105 以高亲和力与TGF- b 1和b 3结合（4）。同种型：鼠IgG1 kappa免疫原：人B谱系白血病细胞的膜制备特异性：抗体SN6识别分子量约为160 kd的人CD105同型二聚体的细胞外表位。据报道它与非人类灵长类动物以及马和猪（11）CD105发生交叉反应。功能应用：抗体SN6将增强TGF-b1与表达CD105的白血病细胞的结合。  抗体SN6已用于鉴定间充质祖细胞群（8,9,10）。