Anaspec/MAPS,核心,8-分支/10 mg/AS-21006

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¥4980.00
货号:AS-21006
浏览量:127
品牌:Anaspec
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商品描述
DescriptionSequence(One-Letter Code)
Product NameMAPS, Core, 8 - BranchK4K2KA - NH2
Size10 mg
Catalog #AS-21006
US$$249
Purity% Peak Area By HPLC ≥ 95%

Multiple Antigenic Peptides (MAPs) are peptides that are branched artificially, in which Lys residues are used as the scaffolding core to support the formation of≤8 branches with varying or the same peptide sequences.It is a method for producing high-titre peptide antibodies and synthetic peptide vaccines. This system utilizes the alpha- and epsilon-amino functional groups of lysine to form a backbone to which multiple peptide chains are attached. Depending on the number of lysine tiers (2, 4, 8, etc.), different numbers of peptide branches can be synthesized. This technology enables successful production of high-titre antibodies. MAPs have a high molar ratio of the peptide antigen to the core molecule, and no carrier protein is needed to elicit an antibody response.

Detailed InformationDatasheet
Material Safety Data Sheets (MSDS)
Storage-20°C
References 1, Wang CY. et al. Science 254:285-288 (1991) 2, Posnett D. et al. J Biol. Chem. 263:1719-1725 (1988) 3, Tam JP. PNAS USA, 85:5409-5413 (1988) 4, Kowasczyk W. et al. J Pept Sci, 17(4):247-251 (2011).
Molecular Weight985.3
K4K2KA-NH2
Sequence(Three-Letter Code)H - (Lys)4 - (Lys)2 - Lys - Ala - NH2
Product CitationsAbboud, N. et al. (2009). Interplay between Akt and p38 MAPK Pathways in the Regulation of Renal Tubular Cell Apoptosis Associated with Diabetic Nephropathy. J Biol Chem 284, 25077.
Anaspec在过去的二十年中,荧光检测生理学和神经学信号受到了极大的关注。使用分子荧光或发光来感测生理和神经信号具有若干优点。其中包括高灵敏度(低至单个分子),开-关切换性,活细胞通信的可行性,具有亚微米可视化的亚纳米空间分辨率和亚毫秒级时间分辨率。光诱导电子转移(PET)和电子能量转移(EET)主要用于将离散的和化学计量的识别事件转换为荧光信号。基于PET效应,开发了许多荧光生理指示剂(如下所述)。AnaSpec提供高质量和具有竞争力的价格的多种生理和神经指标(例如Fura-2,Indo-1和Rhod-2),用于各种生物学应用。AnaSpec努力提供可在任何地方使用的最高纯度的指标。通过HPLC分析,我们的UltraPure级AM荧光指示剂酯的纯度通常至少为95%,尽管纯度通常超过98%。此外,我们还为您提供许多Ca2 +指示剂的AM酯的定制包装服务,以最小的费用为您提供便利,并降低了存储期间变质的风险。