Anaspec/胰高血糖素样肽1,GLP-1(7-37)/0.5mg/AS-20761

价格
¥3180.00
货号:AS-20761
浏览量:88
品牌:Anaspec
服务
全国联保
正品保证
正规发票
签订合同
商品描述
DescriptionSequence(One-Letter Code)
Product NameGlucagon - Like Peptide 1, GLP - 1 (7 - 37)HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Size0.5 mg
Catalog #AS-20761
US$$159
Purity% Peak Area By HPLC ≥ 95%

GLP-1 (7-37) is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It is the cleavage product of proglucagon. Both GLP-1 (7-36) andGLP-1 (7-37) play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. Although GLP-1 (7-37) is bioactive, it is available in lesser amounts than GLP-1 (7-36) and is not amidated.

Detailed InformationMaterial Safety Data Sheets (MSDS)
Storage-20°C
ReferencesBrubaker, P. and D. Drucker, Receptors Channels 8, 179 (2002)Leonova, J. et al. Am J Physiol Cell Physiol 281, C1495 (2001)Drucker, D. et al. Proc Natl Acad Sci USA 84, 3434 (1987)Rönnbäck, L. and E. Hansson, J Neuroinflamm 1, 22 (2004)Rothstein, JD. et al. Neuron 16, 675 (1996)
Molecular Weight3355.7
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Sequence(Three-Letter Code)H - His - Ala - Glu - Gly - Thr - Phe - Thr - Ser - Asp - Val - Ser - Ser - Tyr - Leu - Glu - Gly - Gln - Ala - Ala - Lys - Glu - Phe - Ile - Ala - Trp - Leu - Val - Lys - Gly - Arg - Gly - OH
Anaspec在过去的二十年中,荧光检测生理学和神经学信号受到了极大的关注。使用分子荧光或发光来感测生理和神经信号具有若干优点。其中包括高灵敏度(低至单个分子),开-关切换性,活细胞通信的可行性,具有亚微米可视化的亚纳米空间分辨率和亚毫秒级时间分辨率。光诱导电子转移(PET)和电子能量转移(EET)主要用于将离散的和化学计量的识别事件转换为荧光信号。基于PET效应,开发了许多荧光生理指示剂(如下所述)。AnaSpec提供高质量和具有竞争力的价格的多种生理和神经指标(例如Fura-2,Indo-1和Rhod-2),用于各种生物学应用。AnaSpec努力提供可在任何地方使用的最高纯度的指标。通过HPLC分析,我们的UltraPure级AM荧光指示剂酯的纯度通常至少为95%,尽管纯度通常超过98%。此外,我们还为您提供许多Ca2 +指示剂的AM酯的定制包装服务,以最小的费用为您提供便利,并降低了存储期间变质的风险。