DescriptionSequence(One-Letter Code)

Product Name	AggreSureᵀᴹβ - Amyloid (1 - 42), HumanDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Size	0.25 mg NET peptide
Catalog #	AS-72216
US$	$271
Purity	>95%
AggreSure™ beta-Amyloid (1-42) peptide is pretreated and tested for aggregation using SensoLyte® ThT Aβ42 Aggregation kit (Cat# 72214). Aggregation Guaranteed!
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Detailed Information	Datasheet Material Safety Data Sheets (MSDS)
Storage	–20°C
Molecular Weight	4514.1
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence(Three-Letter Code)	H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH
Product Citations	Cheng, Q. et al (2018). TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer"s disease variant Trem2(R47H) on murine myeloid cell function. J Biol Chem 293(32):12620-12633. doi: 10.1074/jbc.RA118.001848.Reinhardt, S. et al. (2018). Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer"s disease hallmarks. Sci Rep 8(1):1329. doi: 10.1038/s41598-018-19577-7.Livadiotis, G. et al (2017). Experimental Analysis of Interacting HT22 Plasma Membrane Cholesterol and β-Amyloid. Advances in Alzheimer"s Disease 6(04):75.Wang, MJ. et al. (2017). Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer"s disease. Alzheimers Res Ther 9(1):98. doi: 10.1186/s13195-017-0324-0.An, SSA. et al. (2017). Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ(42). Alzheimers Res Ther 9(1):86. doi: 10.1186/s13195-017-0310-6.

Anaspec在过去的二十年中，荧光检测生理学和神经学信号受到了极大的关注。使用分子荧光或发光来感测生理和神经信号具有若干优点。其中包括高灵敏度（低至单个分子），开-关切换性，活细胞通信的可行性，具有亚微米可视化的亚纳米空间分辨率和亚毫秒级时间分辨率。光诱导电子转移（PET）和电子能量转移（EET）主要用于将离散的和化学计量的识别事件转换为荧光信号。基于PET效应，开发了许多荧光生理指示剂（如下所述）。AnaSpec提供高质量和具有竞争力的价格的多种生理和神经指标（例如Fura-2，Indo-1和Rhod-2），用于各种生物学应用。AnaSpec努力提供可在任何地方使用的最高纯度的指标。通过HPLC分析，我们的UltraPure级AM荧光指示剂酯的纯度通常至少为95％，尽管纯度通常超过98％。此外，我们还为您提供许多Ca2 +指示剂的AM酯的定制包装服务，以最小的费用为您提供便利，并降低了存储期间变质的风险。