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小胶质细胞是位于大脑和脊髓中的巨噬细胞，负责中枢神经系统 (CNS) 的免疫防御。由于小胶质细胞与巨噬细胞同源，因此这两类细胞的许多标记物都相同。本指南介绍了小胶质细胞的常用标记物，并重点介绍了全新的小胶质细胞特异性标记物 TMEM119。
TMEM119
TMEM119 是一种细胞表面蛋白，同时也是鼠源和人源小胶质细胞的特异性标记物。TMEM119 的特点是其不在巨噬细胞或其他免疫/神经细胞上表达，这一点不同于其他小胶质细胞标记物。
经抗-TMEM119（绿色）(ab209064) 抗体染色的小鼠脑组织切片。
浏览全部 TMEM119 抗体
单击此处了解有关小胶质细胞亚型和标记物的更多信息。
参考文献
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