Gene Symbol:APPNCBI Gene Id:54226Protein Name:Amyloid beta A4 proteinSwissprot Id:P08592Protein Accession #:NP_062161.1Replacement Item:This antibody may replace item sc-117075 from Santa Cruz Biotechnology.Description of Target:A large body of evidence has implicated the amyloid precursor protein (APP) in the pathogenesis of Alzheimer's disease (AD) (Kamenetz et al., 2003). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD (Liu et al., 2003; Ando et al., 2001).Molecular Weight:~115kDaHost:Rabbit Clonality:PolyclonalPurification:Prepared from rabbit serum by affinity purification on a column made with the C-terminal peptide used as antigen.Application:WBTissue Tool:Find tissues and cell lines supported by DNA array analysis to express APP. 
RNA Seq:Find tissues and cell lines supported by DNA array analysis to express APP. 
Immunogen:Peptide corresponding to amino acid residues from the C-terminal region of rat APP.Predicted Species Reactivity:Dog, Human, Mouse, RatPredicted Homology Based on Immunogen Sequence:Dog; Human; Mouse; RatProduct Format:Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.Reconstitution and Storage:Store at -20C; stable for at least one year.Datasheets/Manuals:Printable datasheet for OAPC00023Specificity:Specific for ~115k APP protein. Immunolabeling of the APP protein band is completely blocked by preadsorption of the antibody with the peptide used as antigen. Aviva为每个蛋白质表达项目提供定制的解决方案。我们专业的科研人员对困难的蛋白质具有丰富的经验，并已生产出2500多种重组蛋白质。无论您的需求是小型研究还是大型cGMP，我们都可以运用我们的经验来满足您的需求。服务包括大肠杆菌表达，哺乳动物表达，酵母表达和抗原制备。
