PredictedSpeciesReactivity:Mouse,RatProductFormat:Liquid.100ulin10mMHEPES(pH7.5),150mMNaCl,100ugpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.Clonality:PolyclonalHost:RabbitApplication:WB,IHCAdditionalInformation:Packaging:100ulin10mMHEPES(pH7.5),150mMNaCl,100ugpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.ReconstitutionandStorage:Forlongtermstorage-20Cisrecommended.Stableat-20Cforatleast1year.GeneSymbol:SLC6A11NCBIGeneId:79213ProteinName:Sodium-andchloride-dependentGABAtransporter3SwissprotId:P31647ProteinAccession#:NP_077348.1DescriptionofTarget:Gamma-aminobutyricacid(GABA)istheprimaryinhibitoryneurotransmitterinthecentralnervoussystem,causingahyperpolarizationofthemembranethroughtheopeningofaCl-channelassociatedwiththeGABAAreceptor(GABAA-R)subtype.GABAplasmamembranetransporters(GATs)influencesynapticneurotransmissionbyhigh-affinityuptakeandreleaseofGABA.Todate,fourdistinctGABAtransportershavebeenidentified:GAT-1,GAT-2,GAT-3,andBGT-1.GAT-3hasbeenfoundtobelocalizedtoastrocyteswithinthecerebralcortexindicatingthatthistransportermediatesGABAuptakeintoglialcells(Minellietal.,1996).MolecularWeight:~67kDaPurification:Preparedfromrabbitserumbyaffinitypurificationviachromatographywithacolumnmadewiththepeptideusedasantigen.TissueTool:FindtissuesandcelllinessupportedbyDNAarrayanalysistoexpressSLC6A11.
RNASeq:FindtissuesandcelllinessupportedbyDNAarrayanalysistoexpressSLC6A11.
Immunogen:PeptidecorrespondingtoaminoacidresiduesfromtheC-terminalregionofratGAT-3.PredictedHomologyBasedonImmunogenSequence:Mouse;RatDatasheets/Manuals:PrintabledatasheetforOAPC00139Specificity:Specificforthe~67kGAT-3protein.Immunolabelingisblockedbythepeptideusedasantigen. Aviva为每个蛋白质表达项目提供定制的解决方案。我们专业的科研人员对困难的蛋白质具有丰富的经验，并已生产出2500多种重组蛋白质。无论您的需求是小型研究还是大型cGMP，我们都可以运用我们的经验来满足您的需求。服务包括大肠杆菌表达，哺乳动物表达，酵母表达和抗原制备。
