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蚂蚁淘在线 / 品牌中心 / avivasysbio / avivasysbio/Anti-TFAM (Transcription Factor A, mitochondrial) (OAPC00069)/OAPC00069/100 ul

avivasysbio/Anti-TFAM (Transcription Factor A, mitochondrial) (OAPC00069)/OAPC00069/100 ul

价格
￥5780.00
货号：OAPC00069-100ul
浏览量：77
品牌：avivasysbio
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商品描述
Gene Symbol:
TFAM
NCBI Gene Id:
21780
Protein Name:
Transcription factor A, mitochondrial
Swissprot Id:
P40630
Protein Accession #:
NP_033386
Nucleotide Accession #:
NM_009360
Replacement Item:
This antibody may replace item sc-166965 from Santa Cruz Biotechnology.
Description of Target:
Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of oxidative stress and mitochondrial dysfunction in microglia (Hayashi et al., 2008). More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice (Morimoto et al., 2012).
Molecular Weight:
~24kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
serum
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TFAM.
RNA Seq:
Find tissues and cell lines supported by DNA array analysis to express TFAM.
Immunogen:
Native recombinant mouse TFAM protein with c-terminal 6-his tag
Predicted Species Reactivity:
Human, Mouse, Rat
Predicted Homology Based on Immunogen Sequence:
Human; Mouse; Rat
Product Format:
Liquid. 100 ul neat serum
Reconstitution and Storage:
Store at -20C in undiluted aliquots; stable for at least 1 year. Avoid freeze/thaw cycles.
Datasheets/Manuals:
Printable datasheet for OAPC00069
Specificity:
Specific for the ~24 kDa TFAM protein.
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