Reconstitution and Storage:Centrifuge the vials after receiving and add 5 μl ddH2OTag:NoneDatasheets/Manuals:Printable datasheet for anti-RAF1 (ANA10389) antibodyGene Symbol:RAF1NCBI Gene Id:5894Description of Target:This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. Nucleotide Accession #:BC018119Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express RAF1. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express RAF1. 
Protein Interactions:Prkab1; FYCO1; NPLOC4; TMEM70; COPS7A; DCAF8; PACSIN3; YWHAQ; RANBP9; RB1; PURA; MAP2K2; MAP2K1; MAPK3; MAPK1; PRKAR1A; MYBPC1; HSP90AA1; AKT1; FAM96B; MRAS; HUWE1; SHOC2; UBC; CDC37; IRS4; GPRASP2; STUB1; SH3KBP1; HIPK4; CDK20; YWHAB; TBXA2R; KRAS; YWHAE Aviva为每个蛋白质表达项目提供定制的解决方案。我们专业的科研人员对困难的蛋白质具有丰富的经验，并已生产出2500多种重组蛋白质。无论您的需求是小型研究还是大型cGMP，我们都可以运用我们的经验来满足您的需求。服务包括大肠杆菌表达，哺乳动物表达，酵母表达和抗原制备。
