avivasysbio/GRIN2A抗体(磷酸-Tyr1246/1252)(OASG05080)/OASG05080/100UL

价格
¥4300.00
货号:OASG05080-100uL
浏览量:76
品牌:avivasysbio
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商品描述
Official Gene Full Name:
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Target:
GRIN2A, GRIN2B
NCBI Gene Id:
2903; 2904; 14811; 14812; 24409; 24410
Swissprot Id:
Q12879, Q13224, P35436, Q01097, Q00959, Q00960
Alias Symbols:
GRIN2A, NMDAR2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2B, NMDAR2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, N
Replacement Item:
This antibody may replace item sc-1468 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
Molecular Weight:
166 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Application:
IHC, IF, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express GRIN2A.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express GRIN2A.
Immunogen:
Synthesized peptide derived from human NMDAEpsilon1/2 around the phosphorylation site of Y1246/1252. Location: 1190-1270aa.
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-GRIN2A (OASG05080) antibody
Target Post-Translational Modification:
Phospho-Tyr1246/1252
Specificity:
Phospho-NMDAEpsilon1/2 (Tyr1246/1252) Polyclonal Antibody detects endogenous levels of NMDAEpsilon1/2 protein only when phosphorylated at Y1246/1252.
Isotype:
IgG
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