avivasysbio/APLP2 Antibody - C-terminal region (ARP87435_P050)/ARP87435_P050/100 ul

价格
¥5780.00
货号:ARP87435_P050-100ul
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品牌:avivasysbio
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商品描述
Gene Symbol:
APLP2
Official Gene Full Name:
amyloid beta precursor like protein 2
NCBI Gene Id:
334
Protein Name:
amyloid-like protein 2
Swissprot Id:
Q06481
Protein Accession #:
NP_001135748.1
Nucleotide Accession #:
NM_001142276.1
Alias Symbols:
APPH, APPL2, CDEBP, APLP-2
Description of Target:
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [
Protein Size (# AA):
763
Molecular Weight:
83 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PLEKHG6.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express APLP2.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human APLP2
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQM
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-APLP2 (ARP87435_P050) antibody is Catalog # AAP87435
Datasheets/Manuals:
Printable datasheet for anti-APLP2 (ARP87435_P050) antibody
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