Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:ORC3Official Gene Full Name:Origin recognition complex, subunit 3NCBI Gene Id:23595Protein Name:Origin recognition complex subunit 3Swissprot Id:Q9UBD5-2Protein Accession #:NP_862820Nucleotide Accession #:NM_181837Alias Symbols:LAT, LATHEO, ORC3, ORC3LDescription of Target:The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.Protein Size (# AA):712Molecular Weight:82kDaPurification:Affinity PurifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express ORC3L. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express ORC3L. 
Predicted Homology Based on Immunogen Sequence:Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 86%Complete computational species homology data:Anti-ORC3L (ARP62223_P050)Peptide Sequence:Synthetic peptide located within the following region: VVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVAConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:ORC5; ORC4; ORC1; MCM7; CDC6; MCM10; ORC6; CCNE2; CDC45; LRWD1; ORC2; APP; SUMO2; XRCC5; UBC; XRCC6; ZBP1; DBF4; ORC3; MCM5; CDK4; TERF2; BRCA1; MCM4;Blocking Peptide:For anti-ORC3 (ARP62223_P050) antibody is Catalog # AAP62223 (Previous Catalog # AAPP48533)Datasheets/Manuals:Printable datasheet for anti-ORC3 (ARP62223_P050) antibodySample Type Confirmation:ORC3 is supported by BioGPS gene expression data to be expressed in HepG2
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