Tested Species Reactivity:HumanProduct Format:Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20Clonality:Monoclonal Clone:ABT-P1Isotype:IgGHost:MouseApplication:IHC-PAdditional Information:Retrieval buffer: Citrate buffer of pH6.0:::Description: Mouse monoclonal to PerforinReconstitution and Storage:Shipped at 4C. Store at -20C. Stable for 12 months at -20C.Immunogen:The antiserum was produced against synthesized peptide derived between 20-60 aa of human PRF1. The exact sequence is proprietary.Purification:Immunogen affinity purifiedDatasheets/Manuals:Printable datasheet for OAAF08384Specificity:Anti-Perforin [ABT-P1] detects endogenous levels of total Perforin protein.Application Info:IHC 1:200 - 1:400Gene Symbol:PRF1Official Gene Full Name:perforin 1Alias Symbols:P1, PFP, HPLH2NCBI Gene Id:5551Protein Name:perforin-1Description of Target:This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood.Swissprot Id:P14222Protein Accession #:NP_001076585.1Nucleotide Accession #:NM_005041.4Molecular Weight:61 kDaTissue Tool:Find tissues and cell lines supported by DNA array analysis to express PRF1. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express PRF1. Aviva为每个蛋白质表达项目提供定制的解决方案。我们专业的科研人员对困难的蛋白质具有丰富的经验，并已生产出2500多种重组蛋白质。无论您的需求是小型研究还是大型cGMP，我们都可以运用我们的经验来满足您的需求。服务包括大肠杆菌表达，哺乳动物表达，酵母表达和抗原制备。
