avivasysbio/Human STAT1 Antibody : SureLight 488 (Phospho-Tyr701) (OAAQ00135)/OAAQ00135

价格
面议
货号:OAAQ00135
浏览量:28
品牌:avivasysbio
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Tested Species Reactivity:
Human, Mouse
Predicted Species Reactivity:
Mouse, Rat
Product Format:
Liquid. 1X PBS, 0.09% NaN3, 0.2% BSA.
Clonality:
Monoclonal
Clone:
Stat1Y701-3E6
Isotype:
Rabbit IgG1k
Host:
Rabbit
Conjugation:
SureLight 488
Application:
FC
Reconstitution and Storage:
2-8C
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr701 of human phospho Stat1
Purification:
Protein A+G
Datasheets/Manuals:
Printable datasheet for OAAQ00135
Target Post-Translational Modification:
Phospho-Tyr701
Application Info:
For flow cytometric staining, the suggested use of this reagent is 5 uL per million cells or 5 uL per 100 uL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
Target Reference:
Ramana CV, Gil MP, Schreiber RD, and Stark GR. (2002) Trends in Immunology. 23: 96-101.Avalle L, Pensa S, Regis G, Novelli F, and Poli V. (2012) JAK-STAT. 1: 65-72.
Gene Symbol:
STAT1
Official Gene Full Name:
signal transducer and activator of transcription 1
Alias Symbols:
CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91
NCBI Gene Id:
6772
Protein Name:
signal transducer and activator of transcription 1-alpha/beta
Description of Target:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Swissprot Id:
P42224
Protein Accession #:
NP_009330.1
Nucleotide Accession #:
NM_007315.3
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express STAT1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express STAT1.
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