avivasysbio/VRK1 Antibody - C-terminal region (ARP96723_P050)/100 ul/ARP96723_P050

价格
¥5780.00
货号:ARP96723_P050
浏览量:69
品牌:avivasysbio
服务
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商品描述
Tested Species Reactivity:
Human
Predicted Species Reactivity:
Human
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
VRK1
Official Gene Full Name:
vaccinia related kinase 1
NCBI Gene Id:
7443
Protein Name:
serine/threonine-protein kinase VRK1
Swissprot Id:
Q99986
Protein Accession #:
NP_003375.1
Nucleotide Accession #:
NM_003384.2
Alias Symbols:
PCH1, PCH1A
Description of Target:
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.
Protein Size (# AA):
396
Molecular Weight:
45 kDa
Purification:
Affinity purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PDIA2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express VRK1.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human VRK1
Peptide Sequence:
Synthetic peptide located within the following region: GGLKAKTITKKRKKEIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-VRK1 (ARP96723_P050) antibody is Catalog # AAP96723
Datasheets/Manuals:
Printable datasheet for anti-VRK1 (ARP96723_P050) antibody
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