Gene Symbol:RNPS1Official Gene Full Name:ribonucleic acid binding protein S1NCBI Gene Id:19826Protein Name:RNA-binding protein with serine-rich domain 1Swissprot Id:Q99M28-2Protein Accession #:NP_001073596.1Nucleotide Accession #:NM_001080127.1Description of Target:Part of pre- and post-splicing multiprotein mRNP complexes. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Enhances the formation of the ATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 and TRA2B/SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Participates in mRNA 3'-end cleavage. Involved in UPF2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Also mediates increase of mRNA abundance and translational efficiency. Binds spliced mRNA 20-25 nt upstream of exon-exon junctions (By similarity).Protein Size (# AA):282Molecular Weight:31 kDaHost:RabbitClonality:PolyclonalPurification:Affinity purifiedApplication:WBTissue Tool:Find tissues and cell lines supported by DNA array analysis to express RNPS1. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express RNPS1. 
Immunogen:The immunogen is a synthetic peptide directed towards the middle region of mouse RNPS1Predicted Species Reactivity:MousePeptide Sequence:Synthetic peptide located within the following region: SSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Concentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-RNPS1 (ARP90731_P050) antibody is Catalog # AAP90731Datasheets/Manuals:Printable datasheet for anti-RNPS1 (ARP90731_P050) antibody Aviva为每个蛋白质表达项目提供定制的解决方案。我们专业的科研人员对困难的蛋白质具有丰富的经验，并已生产出2500多种重组蛋白质。无论您的需求是小型研究还是大型cGMP，我们都可以运用我们的经验来满足您的需求。服务包括大肠杆菌表达，哺乳动物表达，酵母表达和抗原制备。
