Sequence MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAEEAQSGGD Source Recombinant. A DNA sequence encoding the human gamma-synuclein sequence was expressed in E. coli. Description Gamma-Synuclein (originally known as a breast cancer specific gene product, BCSG1) is an acidic neuronal protein of 127 amino acids. It is up-regulated in the majority of late-stage breast and ovarian cancers. Gamma-synuclein may be a potential marker for both late stage breast and ovarian cancers. More recently, it has been shown that gamma-synuclein promotes cancer cell survival and inhibits stress- and chemotherapy drug- induced apoptosis by modulating MAP kinase pathways. Molecular Mass 13,300 Da Purity >95% by SDS-PAGE and Mass Spec.

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