ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. It’s interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Individuals heterozygous for the ApoE4 allele are at higher risk of late-onset Alzheimer’s disease. Recombinant human ApoE4 is a 34.4 kDa protein containing 300 amino acid residues (Accession No. AAB59397). rPeptide is a biotechnology company providing a range of research products and services, with a focus on products for Alzheimer\'s and Parkinson\'s disease research. 阿尔茨海默氏症及帕金森症相关产品       货号 品名 包装 报价 品牌 A-1001-1 Beta-Amyloid （1-40）, Ultra Pure, TFA 0.5 mg 2040 rpeptide A-1001-2 Beta-Amyloid （1-40）, Ultra Pure, TFA 1.0 mg 3400 rpeptide A-1002-1 Beta-Amyloid （1-42）, Ultra Pure, TFA 0.5 mg 2975 rpeptide A-1002-2 Beta-Amyloid （1-42）, Ultra Pure, TFA 1.0 mg 5100 rpeptide A-1003-1 Beta-Amyloid （1-40, Scrambled） 0.5 mg 2550 rpeptide A-1003-2 Beta-Amyloid （1-40, Scrambled） 1.0 mg 4675 rpeptide A-1004-1 Beta-Amyloid （1-42, Scrambled） 0.5 mg 3740 rpeptide A-1004-2 Beta-Amyloid （1-42, Scrambled） 1.0 mg 5950 rpeptide A-1005-1 Beta-Amyloid （1-43）, Ultra Pure, TFA 0.5 mg 3740 rpeptide A-1005-2 Beta-Amyloid （1-43）, Ultra Pure, TFA 1.0 mg 6375 rpeptide A-1007-1 Beta-Amyloid （1-40）, Mouse, Rat  0.5 mg 3825 rpeptide A-1008-1 Beta-Amyloid （1-42）, Mouse, Rat  0.5 mg 4845 rpeptide A-1011-1 Beta-Amyloid （1-40, F4W） 100 ug 1530 rpeptide A-1011-2 Beta-Amyloid （1-40, F4W） 1.0 mg 8075 rpeptide A-1012-1 Beta-Amyloid （1-40, Y10W） 100 ug 1530 rpeptide A-1012-2 Beta-Amyloid （1-40, Y10W） 1.0 mg 8075 rpeptide A-1013-1 Beta-Amyloid （1-40, D23N） 100 ug 1530 rpeptide A-1013-2 Beta-Amyloid （1-40, D23N） 1.0 mg 8075 rpeptide A-1021-1 Beta-Amyloid （1-42, M35V） 100 ug 1700 rpeptide A-1021-2 Beta-Amyloid （1-42, M35V） 1.0 mg 9775 rpeptide A-1022-1 Beta-Amyloid （1-42, R5G） 100 ug 1700 rpeptide A-1022-2 Beta-Amyloid （1-42, R5G） 1.0 mg 9775 rpeptide A-1023-1 Beta-Amyloid （1-42, Y10A） 100 ug 1700 rpeptide A-1023-2 Beta-Amyloid （1-42, Y10A） 1.0 mg 9775 rpeptide A-1024-1 Beta-Amyloid （1-42, F4W） 100 ug 1700 rpeptide A-1024-2 Beta-Amyloid （1-42, F4W） 1.0 mg 9775 rpeptide A-1025-1 Beta-Amyloid （1-42, H6A） 100 ug 1700 rpeptide A-1025-2 Beta-Amyloid （1-42, H6A） 1.0 mg 9775 rpeptide A-1026-1 Beta-Amyloid （1-42, H13A） 100 ug 1700 rpeptide A-1026-2 Beta-Amyloid （1-42, H13A） 1.0 mg 9775 rpeptide A-1027-2 Beta-Amyloid （1-42, H14A） 1.0 mg 9775 rpeptide A-1051-1 Beta-Amyloid （1-11） 1 mg 1530 rpeptide A-1051-2 Beta-Amyloid （1-11） 5 mg 4760 rpeptide A-1052-1 Beta-Amyloid （1-16） 1 mg 1683 rpeptide A-1052-2 Beta-Amyloid （1-16） 5 mg 5440 rpeptide A-1053-1 Beta-Amyloid （1-28） 0.5 mg 1955 rpeptide A-1053-2 Beta-Amyloid （1-28） 1.0 mg 3145 rpeptide A-1055-1 Beta-Amyloid （11-22） 1 mg 1870 rpeptide