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These preformed fibrils of tau-441 may be used as a model for the pathogenic form of tau in numerous tauopathies. Sourced from E. coli, tau-441 fibrils were prepared and confirmed by thioflavin assay and electron microscopy, which shows an average size ranging from 50nm-200nm. Applications of this product range from in vitro studies on fibril formation and stability 1 to in vivo studies on cellular uptake, cell viability and pathway activation 2. This product is also suitable for use in mouse models for studies involving memory, neuronal health, or seeding and prion like spreading 3. Recent assessment of the Amyloid hypothesis has led to the realization that wildtype tau is accumulated in various tauopathies including Alzheimer’s disease, Pick’s disease, and progressive supranuclear palsy among others. Applied to either in vivo or in vitro experiments, these fibrils may be utilized to investigate the mechanism of various tauopathies.
rPeptide is a biotechnology company providing a range of research products and services, with a focus on products for Alzheimer\'s and Parkinson\'s disease research. 阿尔茨海默氏症及帕金森症相关产品 货号 品名 包装 报价 品牌 A-1001-1 Beta-Amyloid (1-40), Ultra Pure, TFA 0.5 mg 2040 rpeptide A-1001-2 Beta-Amyloid (1-40), Ultra Pure, TFA 1.0 mg 3400 rpeptide A-1002-1 Beta-Amyloid (1-42), Ultra Pure, TFA 0.5 mg 2975 rpeptide A-1002-2 Beta-Amyloid (1-42), Ultra Pure, TFA 1.0 mg 5100 rpeptide A-1003-1 Beta-Amyloid (1-40, Scrambled) 0.5 mg 2550 rpeptide A-1003-2 Beta-Amyloid (1-40, Scrambled) 1.0 mg 4675 rpeptide A-1004-1 Beta-Amyloid (1-42, Scrambled) 0.5 mg 3740 rpeptide A-1004-2 Beta-Amyloid (1-42, Scrambled) 1.0 mg 5950 rpeptide A-1005-1 Beta-Amyloid (1-43), Ultra Pure, TFA 0.5 mg 3740 rpeptide A-1005-2 Beta-Amyloid (1-43), Ultra Pure, TFA 1.0 mg 6375 rpeptide A-1007-1 Beta-Amyloid (1-40), Mouse, Rat 0.5 mg 3825 rpeptide A-1008-1 Beta-Amyloid (1-42), Mouse, Rat 0.5 mg 4845 rpeptide A-1011-1 Beta-Amyloid (1-40, F4W) 100 ug 1530 rpeptide A-1011-2 Beta-Amyloid (1-40, F4W) 1.0 mg 8075 rpeptide A-1012-1 Beta-Amyloid (1-40, Y10W) 100 ug 1530 rpeptide A-1012-2 Beta-Amyloid (1-40, Y10W) 1.0 mg 8075 rpeptide A-1013-1 Beta-Amyloid (1-40, D23N) 100 ug 1530 rpeptide A-1013-2 Beta-Amyloid (1-40, D23N) 1.0 mg 8075 rpeptide A-1021-1 Beta-Amyloid (1-42, M35V) 100 ug 1700 rpeptide A-1021-2 Beta-Amyloid (1-42, M35V) 1.0 mg 9775 rpeptide A-1022-1 Beta-Amyloid (1-42, R5G) 100 ug 1700 rpeptide A-1022-2 Beta-Amyloid (1-42, R5G) 1.0 mg 9775 rpeptide A-1023-1 Beta-Amyloid (1-42, Y10A) 100 ug 1700 rpeptide A-1023-2 Beta-Amyloid (1-42, Y10A) 1.0 mg 9775 rpeptide A-1024-1 Beta-Amyloid (1-42, F4W) 100 ug 1700 rpeptide A-1024-2 Beta-Amyloid (1-42, F4W) 1.0 mg 9775 rpeptide A-1025-1 Beta-Amyloid (1-42, H6A) 100 ug 1700 rpeptide A-1025-2 Beta-Amyloid (1-42, H6A) 1.0 mg 9775 rpeptide A-1026-1 Beta-Amyloid (1-42, H13A) 100 ug 1700 rpeptide A-1026-2 Beta-Amyloid (1-42, H13A) 1.0 mg 9775 rpeptide A-1027-2 Beta-Amyloid (1-42, H14A) 1.0 mg 9775 rpeptide A-1051-1 Beta-Amyloid (1-11) 1 mg 1530 rpeptide A-1051-2 Beta-Amyloid (1-11) 5 mg 4760 rpeptide A-1052-1 Beta-Amyloid (1-16) 1 mg 1683 rpeptide A-1052-2 Beta-Amyloid (1-16) 5 mg 5440 rpeptide A-1053-1 Beta-Amyloid (1-28) 0.5 mg 1955 rpeptide A-1053-2 Beta-Amyloid (1-28) 1.0 mg 3145 rpeptide A-1055-1 Beta-Amyloid (11-22) 1 mg 1870 rpeptide

