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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
AboutInVivoMAbanti-mouse4-1BB(CD137)
The17B5monoclonalantibodyreactswithmouse4-1BB,aTNFreceptorsuperfamilymemberalsoknownasCD137.4-1BBisa39kDatransmembraneproteinexpressedbyTlymphocytes,NKcells,dendriticcells,granulocytes,andmastcells.Uponbindingitsligand4-1BBL,4-1BBprovidescostimulatorysignalstobothCD4andCD8TcellsthroughtheactivationofNF-κB,c-Junandp38downstreampathways.Theimportanceofthe4-1BBpathwayhasbeenunderscoredinseveraldiseases,includingcancer.The17B5antibodyhasbeenshowntoblock4-1BB-mediatedTcellproliferationinvitro.
InVivoMAbanti-mouse4-1BB(CD137)Specifications
| Isotype | SyrianHamsterIgG |
| RecommendedIsotypeControl(s) | InVivoMAbpolyclonalSyrianhamsterIgG(BE0087) |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH7.0DilutionBuffer(IP0070) |
| Immunogen | Notavailableorunknown |
| ReportedApplications |
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| Endotoxin |
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| Purity |
|
| Formulation |
|
| Sterility | 0.2µmfiltration |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinA |
| Storage | Theantibodysolutionshouldbestoredatthestockconcentrationat4°C.Donotfreeze. |
| RRID | AB_2687819 |
| MolecularWeight | 150kDa |
