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Branched Polyethylenimine,, Mw 70,000, 30% w/v aq. soln. (bPEI 70000 soln.) is highly branched polyamine with high cationic charge density. bPEI 70000 contains primary, secondary, and tertiary amine groups in approximately 25/50/25 ratio.Industrially, branched polyethylenimine (bPEI) have extensive applications as an auxiliary agent intensifying manufacturing processes and improving quality of the final products. They are widely used in: paper-making, water treatment, detergents, adhesives, and cosmetics. In research, they are extensively investigated as non-viral vector carriers.
转染技术新宠-Polysciences阳离子聚合物基因转染技术 其优点:适用宿主广泛,操作简便,细胞毒性小,转染率高。其中聚乙烯亚胺(PEI)的转染性能最好。聚乙烯亚胺是一种具有较高的阳离子电荷密度的有机大分子,每相隔两个碳原子,就是第三个原子都是质子化的氨基氮原子,使得聚合物网络在任何PH下都能充当有效的“质子海绵”体。这种聚阳离子能将各种报告基因转入各种种属细胞,其效果好于脂质聚酰胺,而且细胞毒性低。大量实验证明,PEI是非常有希望的基因治疗载体。目前在设计更复杂的基因载体时,PEI经常做为核心组成成分。

