Volume: Purified: 100 µL; Purified Trial: 20 µL; TC Supernatant: 5 mL

Concentration: Purified: 1 mg/mL; TC Supernatant: Lot Specific

Clonality: Monoclonal

Form: Purified and TC Supernatant Available (select your preferred form, size and quantity before clicking "Add to Cart")

Host Species: Mouse

Immunogen: Fusion protein amino acids 428-499(cytoplasmic C-terminus) of rat Kv1.2 (accession number P63142), Epitope mapped to within amino acids 463-480Human: 100% identityMouse: 100% identity

Target Description: Kv1.2 K+ channel (Potassium voltage-gated channel subfamily A member 2), which is encoded by KCNA2 gene, is part of the Potassium voltage-gated channel family. Kv1.2 K+ channel switches between its open and closed conformation in response to the voltage difference across the membrane, which selectively allows the traffic of K+. Kv1.2 K+ channel determines potassium ion permeability of excitable membranes according to their electrochemical gradient. Therefore, this protein has for function to regulate neurotransmitter release, neuronal excitability, smooth muscle contraction, heart muscle contraction or insulin secretion. Kv1.2 is recognized as a tansmembrane/ multi-pass membrane protein. Anti-Kv1.2 K+ channel K14/16 is often used in IHC on human normal cerebral cortex.

Gene ID: KCNA2

Antibody Registry ID (RRID): AB_2296313

Physical State: Liquid

Validation and Application Notes

Molecular Weight: 80 kDa

NOTE

Aves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.

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二抗 该系列产品特点在于鸡IgY分子与哺乳动物IgG分子截然不同，因此由之制备的二抗不与来源于兔、小鼠或其他哺乳动物的一抗产生交叉反应，特别适用于组织学的免疫双标检测。该系列源于羊的二抗可交联荧光基团/HRP/生物素/琼脂糖，可广泛用于WB，免疫组化/免疫细胞化学及免疫共沉淀研究。