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H3K79me2MouseMonoclonalAntibody
| Clonality:MouseIG1 | Source:Mouse | |
| Applications:WB:1:500-1:2000 | Cross-Reactivity:HMRat; | |
| Concentration:100ug/100ul | Detectedband(bywestern)MW:15kD | |
Alt.Names
H3histoneantibody,HIST1H3Aantibody,Histonecluster1,H3aantibody
Specificity:
TheHistoneH3(dimethylK79)mousemonoclonalantibodycanrecognizeendogenousHistoneH3(dimethylK79)proteins.
Immunogen:
MousemonoclonalantibodyispreparedbyimmunizingsyntheticpeptidecoupledtoKLH.
StorageConditionandBuffer:
Storeat-20°C.Stableforoneyearfromthedateofshipment.1mg/mlinPBS,pH7.4,containing0.02%sodiumazideand50%glycerol
H3K79methylationisoneofthegeneactivationMarkers.DOT1LmethyltransferaseusuallyinvolvesinH3K79methylation,playingessentialrolesinembryonicdevelopment,hematopoiesis,cardiacfunctionandthedevelopmentofleukemia.
TodetectmarkerH3K79methylationstatus,pickfromourH3K79polyclonalantibodyseriesorH3K79mousemonoclonalantibodyseries.
H3K79me2_monocolonal_Antibody.pdf
SDS_H3K79me2_Mouse_Monoclonal_Antibody.pdf
References:
1.RobertACopeland.Proteinmethyltransferasesincancer.(2013)AACRAnnualMeeting.
2.RoyMPollock.PreclinicalCharacterizationofaPotent,SelectiveInhibitoroftheProteinMethyltransferaseDOT1LforUseintheTreatmentofMLL-RearrangedLeukemia.(2012)54thASHAnnualMeetingandExposition.
Productisforresearchuseonly.Notforhumanuse.
