Xcessbio/H3K79me1小鼠单克隆抗体Xcessbio Biosciences Inc/5ug/A90001-5

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货号:A90001-5
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品牌:Xcess
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ProductInformation

H3K79me1MouseMonoclonalAntibody

CatalogNo:A90001Species:Mouse

Concentration:100ug/100ulClonality:MouseIgG1

Applications:WB1:500-1:2000Reactivity:Human,Mouse,Rat

Detectedband(bywestern)molecularweight:15kD

Alt.Names

H3histoneantibody,HIST1H3Aantibody,Histonecluster1,H3aantibody

Specificity:

TheHistoneH3(monomethylK79)mousemonoclonalantibodycanrecognizeendogenous

HistoneH3(monomethylK79)proteins.

Immunogen:

MousemonoclonalantibodyispreparedbyimmunizingsyntheticpeptidecoupledtoKLH.

StorageConditionandBuffer:

Storeat-20°C.Stableforoneyearfromthedateofshipment.

1mg/mlinPBS,pH7.4,containing0.02%sodiumazideand50%glycerol

Background:

H3K79methylationisoneofthegeneactivationMarkers.DOT1LmethyltransferaseusuallyinvolvesinH3K79methylation,playingessentialrolesinembryonicdevelopment,hematopoiesis,cardiacfunctionandthedevelopmentofleukemia.

TodetectmarkerH3K79methylationstatus,youcanalsopickfromourH3K79polyclonalantibodyseries.

PDF:

H3K79me1_Mouse_Monoclonal_Antibody.pdf

SDS:

SDS_H3K79me1_Mouse_Monoclonal_Antibody.pdf

References:

1.RobertACopeland.Proteinmethyltransferasesincancer.(2013)AACRAnnualMeeting.

2.RoyMPollock.PreclinicalCharacterizationofaPotent,SelectiveInhibitoroftheProteinMethyltransferaseDOT1LforUseintheTreatmentofMLL-RearrangedLeukemia.(2012)54thASHAnnualMeetingandExposition.

Forresearchuseonly.Notforhumanuse.

Xcess生物科学公司(XcessBio)成立于2008年,由一群顶尖的科学家来自学术界和制药/生物技术产业具有较强的专业知识在药物化学、生物化学、分子和细胞生物学。