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商品描述
Adrm1isanintegralUbreceptorofthe26Sproteasome.Adrm1bindsbothUbandpolyUbchainsviaitsN-terminalPrudomain.ThePrudomainalsobindsS1tolocateAdrm1onthe26Sproteasome.TheC-terminaldomainofAdrm1bindsandactivatesthedeubiquitinatingenzymeUch37,thoughwhichUch37isrecruitedtothe26Sproteasome.Currently,itisnotknownwhetherAdrm1activatesUch37todeubiquitinatepolyUbchains.
AdditionalInformation
| ProductName: | Adrm1/Uch37 |
|---|---|
| AlsoKnownAs: | Adrm1(ADRM1;ARM1;GP110;Rpn13);Uch37(UCHL5;UCH37;CGI-70;INO80R;UCH-L5) |
| CatalogNo.: | A3601 |
| Size: | 100µg |
| MolecularWeight: | Adrm1(42,2kDa),Uch37(37.6kDa) |
| Species: | Human |
| Source: | Bacterialrecombinant |
| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
| Concentration: | Seetubelabel |
| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
| PDFDataSheet: | PDFDatasheet,MSDS |
| NCBIRefSeq: | NM_007002(Adrm1),NM_015984(Uch37) |
| Image(s): | N/A |
| ShippingMethod: | Dryiceshipping |
| References: | 1.VermaR,etal.(2000)MolBiolCell11(10),3425–3439. 2.KoulichE,etal.(2007)MolBiolCell,19(3)1072–1082.3.HusnjakK,etal.(2008)Nature453,481–488. 4.LeeBH,etal.(2010)Nature467,179–184. |


