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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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商品描述
VE-821isapotentandselectiveATPcompetitiveinhibitorofataxia-telangiectasiaandRad3-relatedprotein(ATR)withIC50of26nMincell-freeassays,withminimalactivityagainstATM,DNA-PK,andmTOR.ItaugmentsDNAdamageandcelldeathofcancercellsinresponsetorADIation,alsosensitizescancercellstochemotherapy.
AdditionalInformation
| ProductName: | VE-821 |
|---|---|
| AlsoKnownAs: | 3-Amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-2-pyrazinecarboxamide |
| CatalogNo.: | F8130 |
| Size: | 5mg |
| CAS: | 1232410-49-9 |
| Formula: | C18H16N4O3S |
| MolecularWeight: | 368.41Da |
| Form: | Lyophilizedpowder |
| QualityAssurance: | >98%byHPLCandNMR |
| Source: | Synthetic |
| Storage: | EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving |
| PDFDataSheet: | DownloadPDFdatasheet |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.ReaperPM,etal.(2011)NatChemBiol,7(7),428-430. 2.Prevo,R,etal.(2012)CancerBiolTher,13(11)1072-1081. 3.Huntoon,CJ,etal.(2013)CancerRes,73(12)3683-3691. |
