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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
IdarubicinHClisahydrochloridesaltformofIdarubicinwhichisananthracyclineantibioticandaDNAtopoisomeraseII(topoII)inhibitorforMCF-7cellswithIC50of3.3ng/mL.Idarubicinisdevelopedinanattempttoreducethecardiotoxicityandenhancethetherapeuticefficacyoftheparentcompound.IdarubicinHClisaninhibitorofTopoIIαandanapoptosisinducer.IdarubicinHCLwasusedat0.1nM-10nMinvariouscell-basedinvitroassays.
AdditionalInformation
| ProductName: | IdarubicinHCl |
|---|---|
| AlsoKnownAs: | 4-demethoxydaunorubicin(NSC256439,4-DMDR)HCl |
| CatalogNo.: | F8100 |
| Size: | 5mg |
| MolecularWeight: | 533.95Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >99%byHPLCandNMR |
| Storage: | EligIBLeforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
| PDFDataSheet: | PDFDatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.FukushimaT,etal.(1993).Int.J.Hematol.57:121-130. 2.Belaud-RotureauMA,etal.(2000).Leukemia.14:1266-1275. 3.OrlandiP,etal.(2005)JChemother.17(6):663-667. 4.ColburnDE,etal.(2004)Hematology.9(3):217-221. |
