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商品描述
Apotent,reversIBLe,cellpermeableandspecificinhibitorofATPaseofp97(alsocalledvalosin-containingprotein(VCP))withIC50of1.5μM.DBeQinhibitsbothubiquitin-dependentandautophagicproteindegradationpathwaysandrapidlyinducescaspases-3and-7activityandapoptosis.
AdditionalInformation
| ProductName: | DBeQ |
|---|---|
| AlsoKnownAs: | N²,N⁴-Dibenzylquinazoline-2,4-diamine;CAS#177355-84-9;C₂₂H₂₀N₄ |
| CatalogNo.: | F1420 |
| Size: | 5mg |
| MolecularWeight: | 340.42Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | ≥98%byHPLC |
| Storage: | Eligibleforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
| PDFDataSheet: | PDFDatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.ChouTF,etal.(2011)ProcNatlAcadSciUSA,108(12),4834-4839.
2.ChouTF,etal.(2011)Autophagy,7(9),1091-1092. |
