品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
MG-132isareversIBLeproteasomeinhibitorthatbelongstothefamilyknownaspeptidealdehydes.MG-132iscellpermeableandcanbeusedtotreatvariousmammaliancellstoblockproteasomeactivities.MG-132canbedissolvedinDMSOforstocksolutionupto100mM.Thetypicalconcentrationsforcellcultureuseare1-10µM.Forinvitrouse,thetypicalconcentrationsare50-100µM.MG132,Z-LLL-al,Z-Leu-Leu-Leu-CHO,CAS#:133407-82-6
AdditionalInformation
| ProductName: | MG-132 |
|---|---|
| AlsoKnownAs: | MG132,Z-LLL-al,Z-Leu-Leu-Leu-CHO,CAS#:133407-82-6 |
| CatalogNo.: | F1100 |
| Size: | 5mg |
| MolecularWeight: | 475.6Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >98%byHPLCandNMR |
| Storage: | Eligibleforroomtemperatureshipping.Storeat-80°Cuponreceiving;avoidmultiplefreeze-thawcyclesafterdissolvinginDMSO. |
| PDFDataSheet: | PDFDatasheet，MSDS |
| NCBIRefSeq: | N/A |
| Image(s): | (Clickimagetoenlarge) 100nMbovine26Sproteasome(Cat.#A1200)wasincubatedwithDMSOorwith10µMMG-132for10minat37°Cin20mMTris,pH7.1,50mMNaCl,2mMATP,5mMMgCl2,2mMbMEand10%glycerol.Theproteasomewasthendiluted10Xinto50µMSUC-LLVY-AMC(Cat.#G1100)inabuffercontaining20mMTris,pH7.1,2mMbME.ThereleasedAMCfluorescencewasmonitoredbyaplatereader.  EqualamountofwholecelllysatespreparedfromDMSO(lane1)or20μMMG132(lane2)-treatedHEK293TcellswereseparatedbySDS-PAGEandimmunoblottedwithananti-Ubantibody.CellsweretreatedwithDMSOorMG-132for4hours. |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.WilkS,etal.(1993)EnzymeProtein47(4–6),306–313. 2.BushDT,etal.(1997)JBiolChem272(14),9086–9092.3.MyungJ,etal.(2001MedResRev21(4),245–273. |
