品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
TNFalpha(Tumornecrosisfactoralpha)isproducedbyimmuneandepithelialcells.Itplaysimportantrolesinregulatinginflammation,apoptosis,andimmuneresponse.ItexertsitsfunctionmainlybybindingoftwocellsurfacereceptorsTNFR1andTNFR2.TreatingcellswithTNFalphaactivatestheNFkappaB,MAPK,anddeathsignalingpathways.TherecombinantTNFalphaproteinconsistsoftheextracellulardomain(aminoacids77-233)offulllengthTNFalpha.Itinducesapoptosisofvariouscancercellsattheconcentrationof10-100ng/mL+1ug/mLcycloheximide(aproteintranslationinhibitor).ItisgeneratedfromGST-TNFalpha(catlog#U1130)byremovaloftheN-terminalGSTtag.
AdditionalInformation
| ProductName: | TNFalpha | ||
|---|---|---|---|
| AlsoKnownAs: | TNF;DIF;TNFA;TNFSF2;TNF-alpha | ||
| CatalogNo.: | U1120 | ||
| Size: | 50µg | ||
| MolecularWeight: | 25.6kDa | ||
| Species: | Human | ||
| Source: | Bacterialrecombinant | ||
| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol | ||
| Concentration: | Seetubelabel | ||
| QualityAssurance: | ~85%bySDS-PAGE | ||
| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles | ||
| PDFDataSheet: | PDFDatasheet | ||
| NCBIRefSeq: | NM_000594.3 | ||
| Image(s): | (Clickimagetoenlarge)
| ||
| ShippingMethod: | Dryiceshipping | ||
| References: | N/A |
 |
| Coomassie-stainedSDS-PAGE Lane1:Molecularweightmarkers Lane2:5µgpurifiedTNFalpha |
