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蚂蚁淘在线 / 品牌中心 / Trevigen / Trevigen/Cultrex®；3D基底膜基质，还原生长因子/3445-001-01/1 ml，2 x 5 ml，5 ml

Trevigen/Cultrex®；3D基底膜基质，还原生长因子/3445-001-01/1 ml，2 x 5 ml，5 ml

价格
￥1000.00
货号：3445-001-01
浏览量：127
品牌：Trevigen
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商品描述

Description

Cultrex®BasementMembraneExtract(BME)isasolubleformofbasementmembranepurifiedfromEngelbreth-Holm-Swarm(EHS)tumor.Thisextractprovidesanaturalextracellularmatrixhydrogelthatpolymerizesat37°Ctoformareconstitutedbasementmembrane.Basementmembranesarecontinuoussheetsofspecializedextracellularmatrixthatformaninterfacebetweenendothelial,epithelial,muscle,orneuronalcellsandtheiradjacentstromaandthatplayanessentialroleintissueorganizationbyinfluencingcelladhesion,migration,proliferation,anddifferentiation.ThemajorcomponentsofBMEincludelaminin,collagenIV,entactin,andheparansulfateproteoglycans.

Cultrex®3DCultureMatrix®RGFBMEisaBasementMembraneMatrixthathasbeendeveloped,producedandqualifiedspecificallyforusein3Dculturestudies.

Qualitycontrolspecifications:

  • Mousecoloniesareroutinelyscreenedforpathogensusing mouseantibodyproduction(MAP)testing.
  • Engelbreth-Holm-Swarm(EHS)tumorisLDEV-free.
  • PathClear®–testednegativebyPCRfor17bacterialandvirusstrainstypicallyincludedinmouseantibodyproduction(MAP)testing,plus13additionalmurineinfectiousagentsincludingLDEV,foratotalof31organismsandviruses.
  • Nobacterialorfungalgrowthdetectedafterincubationat37°Cfor14daysfollowingUSPsterilitytestingguidelines.
  • Endotoxinconcentration≤8EU/mlbyLimulusAmoebocyteLysate(LAL)assay.
  • Proteinconcentrationof14–16mg/ml.
  • NomycoplasmacontaminationdetectedbyPCR.
  • ProvidedinDulbecco’sModifiedEagle’smedium(DMEM)withoutphenolred,with10µg/mlgentamicinsulfate.
  • GelstABIlitytestedforaperiodof14daysat37°C.
  • BIOLOGicalactivitydeterminedforeachlot:
    • Tubeformationassay–BMEpromotesformationofcapillary-likestructuresbyhuman(HBMVEC;HUVEC)ormouse(SVEC4-10)endothelialcells.
    • 3DCulture:BasementMembraneExtractpromotesdifferentiationofahumanepithelialcelllinederivedfrommammarygland(MCF-10A)orhumanprostate(PC-3)intoacinarstructures.
Catalog#3445-010-01includes:
CatalogNumberDescriptionQty
3445-005-013-DCultureMatrix™ReducedGrowthFactorBasementMembraneExtract,PathClear®2

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Chih-ChienChou,Kuen-HaurLee,I-LuLai,DashengWang,XiaokuiMo,SamuelK.Kulp,CharlesL.Shapiro,andChing-ShihChen
CancerRes.,Sep2014;74:4783–4795.
http://cancerres.aacrjournals.org/cgi/content/abstract/74/17/4783

Silencingβ3IntegrinbyTargetedECO/siRNANanoparticlesInhibitsEMTandMetastasisofTriple-NegativeBreastCancer
JennyG.Parvani,ManeeshD.Gujrati,MargaretA.Mack,WilliamP.Schiemann,andZheng-RongLu
CancerRes.,Jun2015;75:2316–2325.
http://cancerres.aacrjournals.org/cgi/content/abstract/75/11/2316

SurvivalOutcomeandEMTSuppressionMediatedbyaLectinDomainInteractionofEndo180andCD147
MercedesRodriguez-Teja,JulianH.Gronau,AiMinamidate,StevenDarby,LukeGaughan,CraigRobson,FrancescoMauri,JonathanWaxman,andJustinSturge
Mol.CancerRes.,Mar2015;13:538–547.
http://mcr.aacrjournals.org/cgi/content/abstract/13/3/538

“Invitrodifferentiationofhumanamnioticepithelialcellsintoinsulinproducing3Dspheroids”
“BernardOkere,FrancescoAlviano,RobertaCosta,DanielaQuaglino,FrancescaRicci,MassimoDominici,PaoloPaolucci,LauraBonsi,andLorenzoIughetti”
InternationalJournalofImmunopathologyandPharmacology
http://iji.sagepub.com/cgi/content/abstract/28/3/390

Trevigen，Inc.是一家发展迅速的生物技术公司，致力于开发用于癌症研究，药物发现，遗传毒理学，再生医学和干细胞研究的产品和技术。我们提供试剂盒和试剂，用于研究DNA损伤和修复，细胞凋亡，氧化应激，癌细胞行为，3D培养和干细胞。该公司获得了美国国立卫生研究院（National Institutes of Health）多项SBIR资助。