Prosci/ACE2抗体[AC18F]/36-031/100微克

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¥6300.00
货号:36-031
浏览量:102
品牌:ProSci
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商品描述

Specifications

SPECIESREACTIVITY:Human
TESTEDAPPLICATIONS:ELISA,Flow,WB
APPLICATIONS:ELISA:(directorindirect:1:2,000-1:10,000).FlowCytometry:(1:1,000).Westernblot:(1:2,000-1:10,000usingECL.SuggestedblockinganddilutionbufferisPBSTwith0.05%Tween20and5%skimmilk.Suggestedincubationtimeis1houratrooomtemperature).Optimalconditionsshouldbedeterminedindividuallyforeachapplication.
USERNOTE:Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
SPECIFICITY:RecognizeshumanACE2.
IMMUNOGEN:RecombinanthumanACE2.
HOSTSPECIES:Mouse

Properties

PHYSICALSTATE:Liquid
BUFFER:Liquid.0.2um-filteredsolutioninPBS,pH7.4.Containsnopreservatives.
CONCENTRATION:1mg/ml
STORAGECONDITIONS:Stableforatleast1yearafterreceiptwhenstoredat-20˚C.
CLONALITY:Monoclonal
ISOTYPE:IgG1,kappa
CONJUGATE:Unconjugated

AdditionalInfo

ALTERNATENAMES:SARSReceptor;Angiotensin-convertingEnzyme2;ACEH
ACCESSIONNO.:NP_068576
PROTEINGINO.:11225609
OFFICIALSYMBOL:ACE2
GENEID:59272

Background

BACKGROUND:ACE2hasdirecteffectsoncardiacfunctions.Itisexpressedpredominantlyinvascularendothelialcellsoftheheartandkidney.ACE2convertsangiotensinItoangiotensin1-9.ACE2wasalsoidentifiedasafunctionalreceptorforSARScoronavirus.
ProSci 研究计划包括癌症生物标记物发现和中和针对新兴病毒(例如HIV和流感)的抗体开发。ProSci的创新方法研究使用基因工程酵母菌株和糖蛋白模拟HIV-1聚糖衣壳并开发针对HIV-1聚糖的中和抗体,已获得NIH的多项小型企业创新研究(SBIR)资助。其研究项目已获得美国专利商标局授予的发明专利,以及许多同行评审的出版物