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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Specifications
| SPECIESREACTIVITY: | Human |
|---|---|
| TESTEDAPPLICATIONS: | ELISA,WB |
| APPLICATIONS: | ACADLantibodycanbeusedfordetectionofACADLbyELISAat1:12500.ACADLantibodycanbeusedfordetectionofACADLbywesternblotat0.25μg/mL,andHRPconjugatedsecondaryantibodyshouldbediluted1:50,000-100,000. |
| USERNOTE: | Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher. |
| POSITIVECONTROL: | 1)Tranfected293TCellLysate |
| PREDICTEDMOLECULARWEIGHT: | 44kDa |
| IMMUNOGEN: | AntibodyproducedinrabbitsimmunizedwithasyntheticpeptidecorrespondingaregionofhumanACADL. |
| HOSTSPECIES: | Rabbit |
Properties
| PURIFICATION: | Antibodyispurifiedbypeptideaffinitychromatographymethod. |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| BUFFER: | AntibodyislyophilizedinPBSbufferwith2%sucrose.Add50μLofdistilledwater.Finalantibodyconcentrationis1mg/mL. |
| CONCENTRATION: | 1mg/ml |
| STORAGECONDITIONS: | Forshortperiodsofstorage(days)storeat4˚C.Forlongerperiodsofstorage,storeACADLantibodyat-20˚C.Aswithanyantibodyavoidrepeatfreeze-thawcycles. |
| CLONALITY: | Polyclonal |
| CONJUGATE: | Unconjugated |
AdditionalInfo
| ALTERNATENAMES: | ACADL,ACAD4,LCAD |
|---|---|
| ACCESSIONNO.: | NP_001599 |
| PROTEINGINO.: | 4501857 |
| OFFICIALSYMBOL: | ACADL |
| GENEID: | 33 |
Background
| BACKGROUND: | ACADLbelongstotheacyl-CoAdehydrogenasefamily,whichisafamilyofmitochondrialflavoenzymesinvolvedinfattyacidandbranchedchainamino-acidmetabolism.Thisproteinisoneofthefourenzymesthatcatalyzetheinitialstepofmitochondrialbeta-oxidationofstraight-chainfattyacid.DefectsinACADLgenearethecauseoflong-chainacyl-CoAdehydrogenase(LCAD)deficiency,leADIngtononketotichypoglycemia.Theproteinencodedbythisgenebelongstotheacyl-CoAdehydrogenasefamily,whichisafamilyofmitochondrialflavoenzymesinvolvedinfattyacidandbranchedchainamino-acidmetabolism.Thisproteinisoneofthefourenzymesthatcatalyzetheinitialstepofmitochondrialbeta-oxidationofstraight-chainfattyacid.Defectsinthisgenearethecauseoflong-chainacyl-CoAdehydrogenase(LCAD)deficiency,leadingtononketotichypoglycemia. |
|---|---|
| REFERENCES: | 1)Lea,W.,Biochim.Biophys.Acta1485(2-3),121-128(2000). |
